Dosage form: In what form will the drug be administered?
Drug – The drug contained within the membrane or in the adhesive.
The transdermal patch design is dictated by the properties of the drug. If you’re working with an active ingredient, you’ve likely already characterized it. These are typically the main areas considered:
For patients and caregivers, it’s a non-invasive, painless way to administer medication that provides a constant therapeutic dosage for a limited period of time.
Backing – The outermost layer of the patch, which protects the formulation during the wear period.
As you’re reviewing material vendors, make sure they have a Drug Master File (DMF) established with the FDA. The Drug Master File is a confidential document provided from a material supplier to the FDA. It provides details on how a product is manufactured.
For example, at one point, the FDA was interested in patients’ abilities to clearly identify the difference between the liner and the patch itself. Regulations were being considered that would require differentiation between the patch and the liner. For example the patch would be opaque and the liner translucent.
“Compatibility between materials and equipment is essential for a smooth commercialization process,” Schubert notes. For example, if a component roll is 48” wide, it is better to run 12” rolls with no waste versus cutting materials into two (2) 17” rolls with a yield loss of 14”.
Whether it’s your company or the vendors you’re working with, make sure a close eye is kept on the evolving FDA guidelines. As Schubert pointed out, they will not only dictate much of your design, but they can also lead to innovation.
Choosing the right materials for transdermal patches requires considering a number of factors.
Whether it’s for treating superficial disorders or for curing systemic ailments, medical patches as a transdermal drug delivery system are now one of the most popular means of caring for the skin and body.
Our team integrates seamlessly with your research and production department so we can actively collaborate on a solution. Our seasoned engineers and operators flawlessly execute the plans that we put into place. We never have complaints, and our products are always made to the most stringent quality standards.
Our experts lead the industry producing patches for:
We deliver end-to-end, customer-focused solutions. Rather than simply return a quote, we want to help build your brand and image. Our collaborative approach combined with our unrivaled transdermal prowess has put us at the top of our industry.
We are unlike any transdermal patch company you’ve ever worked with.
Our process efficiency, experience in the industry, and state-of-the-art facilities give us the power to turn your dreams into a working entity in a matter of weeks rather than months.
We are transforming the medical patch industry through sophisticated custom solutions made in our state-of-the-art facilities in the USA. We work side by side with our partners in the healthcare industry from initial concepts to final products, offering our unrivaled expertise along the way. Together, we can change our industry and the lives of millions of patients around the world.
All of our products are held to the strictest quality criteria for maximum deliverability and safety.
We work with you in mind. That means we are always here to answer questions and provide value-added services. We don’t just return you a quote; we take proactive steps to drastically increase your efficiency and reduce expenditures.
TRANSDERMAL PATCH MANUFACTURER R & D Wearable Medical Device Adhesives R&D Medical Products is one of the world’s leading transdermal patch manufacturers. Our mission is to deliver