The biggest concern Rosania has right now is the quality of the available products.
Dr. McGeorge can be seen on Local 4 News helping Metro Detroiters with health concerns when he isn’t helping save lives in the emergency room at Henry Ford Hospital.
“The products that are currently being sold are unregulated, so we don’t even know if those products contain the CBD they are said to contain. We also don’t know whether there’s other contaminants that may be present,” he said.
According to University of Michigan College of Pharmacy Professor Gus Rosania, “We are getting closer to actually being able to study hemp and hemp derived CBD and what it’s doing.”
“The varieties that produce low levels of THC, below 0.3 percent dry weight, those varieties are considered hemp,” Rosania said.
In addition to the unsubstantiated claims of CBD’s effectiveness at treating a wide range of medical conditions, the FDA has other concerns. Some of the questions that remain include, what are the safe dose limits, what is the full side effect profile, what is the effect of long-term use, what effect is there in children or pregnant women and what is the extent of drug interactions.
CBD stands for cannabidiol. It’s one of dozens of substances called cannabinoids produced by the cannabis plant. The most familiar cannabinoid is THC, the compound in cannabis that has the effect of getting a person high. It’s different than CBD.
“There is very little harmful effect, there is sleepiness associated with it or there’s sleep disturbances, but what’s more of a serious concern is coming from drug-drug interactions,” Rosaina said.
The CBD industry has grown since the legalization of hemp, but many questions remain. The FDA does have regulatory authority over CBD, especially since cannabidiol had been approved for the treatment of certain forms of epilepsy.
A few years ago hardly anyone had ever even heard of CBD. Now it's showing up in supplements, foods and even makeup.
Moyad is considered one of the world’s leading experts on supplements, and he’s got some concerns. One is quality control. If you’re buying CBD, ask for a COA.
“Which means it’s possible for CBD to increase the amount of another drug you’re taking to a dangerous level, or decrease that,” he explains. “So the chance for liver toxicity when you’re combining CBD with other prescription meds, and maybe even supplements, is higher than normal.”
Another concern for Dr. Moyad is the possible of drug-to-drug interaction.
CBD has worked in treating seizures in certain epilepsy patients, but what else can it do? More research is still being done.
“So what we’re seeing in clinical trials is a placebo response rate is extremely high. People taking it for all sorts of conditions and immediately going, ‘Hey, this works! This is incredible!’ and this kind of gets discounted,” Moyad said. “So this is why you want to wait for the hype to go down a little bit, to see what it really works for, what it’s dangerous for, and where it does nothing.”
Moyad says wait for the hype to die down a little and wait for more published research to know exactly what the benefits are.
CBD is sweeping the nation and the accompanying hype has made it a difficult thing to ignore. CBD is extracted from flowers or buds of marijuana. It’s not the compound that gets you high, but it does have many medical uses. However, if you’re going to be ingesting the ingredient you should know where to buy it and that’s not always easy. Dr. Mark Moyad from the University of Michigan explains what you need to know.
“A COA is a certificate of analysis. This is proof by a third party that what they’re selling you is actually in the container itself. If the clinic or the place that you go says, ‘What’s a COA?’ or ‘We can’t provide the COA,’ you may want to run, and run away quickly,” Dr. Moyad says.
But how do you know what you’re really getting? There are three letters you need to know.
You've probably heard of CBD – it's everywhere. The compound, which is extracted from marijuana buds and flowers is used to treat pain and disorders like epilepsy. However, with the hype reaching a fever pitch, it'll help to know where it's best to buy the product if you plan on using it. Dr. Mark Moyad of the University of Michigan explains what to look out for.