CBD Oil For Dogs With Cushing’s


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Both dogs and humans are susceptible to Cushing’s disease. Middle-aged and older dogs are more likely to develop the disease. Explore CBD oil for dogs with Cushing's disease that can help relieve stress, nausea, and pain. Discover all the benefits today! Can you treat canine Cushing’s Disease with CBD? Learn about Cushing’s Disease and discover how to bring relief to your canine friend by using CBD oil.

CBD oil for dogs with Cushing’s disease

In dogs, hyperadrenocorticism or Cushing’s Disease occurs due to an overabundance of the hormone cortisol.

Cortisol comes from the adrenal glands, which are found above the kidneys in mammals.

Both dogs and humans are susceptible to Cushing’s disease. Middle-aged and older dogs are more likely to develop the disease, with risk categories beginning around the age of six.

According to Washington State University, an estimated 100,000 dogs are diagnosed with Cushing’s disease in the United States every year.

Cortisol: An explainer

The mainstream understanding of cortisol is related to the concept of stress—which is partly true. In a healthy body, cortisol is released when waking up, exercising, or going through some form of exertion. It also plays a role in signaling the fight or flight response.

But the true role of cortisol in the body is much wider. According to the FDA’s Center for Veterinary Medicine, cortisol can be thought of as a natural steroid, not only helping the body adapt to stress but also regulating body weight, tissues, skin health, and a host of other features of related to proper functioning, such as the metabolism and blood pressure.

Too much cortisol in the body and the immune system is likely to become stressed, which in turn makes animals and humans more susceptible to outside infections. When the adrenal glands consistently overproduce cortisol, the body can also begin to experience other forms of disruption, which will continue to worsen until cortisol levels are reduced.

What does Cushing’s disease look like in dogs?

Most of the time, Cushing’s has a slow onset, meaning that owners may not know exactly when symptoms begin to emerge in their dog. According to VCA Hospitals, by the time that symptoms are noticeable, they usually include:

Thirst to the point of franticness

Increased urination (often as a result of overhydration)

Large increases or decreases in appetite (stress eating)

Lethargy, listlessness, and reduced activity

Panting without a clear reason

Thinner skin, noticeable upon picking a dog up

Hair loss, primarily on the body rather than legs

An enlarged abdomen that results in a ‘potbelly’ appearance

How is it treated by veterinarians?

Treatment for Cushing’s will depend partly on the source behind your dog’s increased cortisol levels.

Pituitary-dependent Cushing’s disease results from disruption to the pituitary gland at the base of the brain—often due to a tumor, trauma, or separate disease. When disrupted, the pituitary gland can overproduce something called the adrenocorticotropic hormone, which in turn signals the adrenal glands to overproduce cortisol. The FDA estimates that up to 85 percent of dogs with Cushing’s have this sort of pituitary-dependent form.

Adrenal-dependent Cushing’s disease results from disruption to the adrenal glands themselves—again, usually due to a tumor. This causes the glands to become confused and overproduce cortisol, which builds in the bloodstream.

Completely curing Cushing’s disease requires removing the tumor or other disruption to the affected gland before the tumor spreads. In adrenal-dependent cases, this may be possible through surgery, however, surgical techniques for the pituitary-dependent disease are not viable options for dogs in the majority of situations.

Most of the time, dogs with Cushing’s will be treated via a lifelong management plan, consisting of courses of medication that are designed to inhibit cortisol production, as well as frequent checkups from their veterinarian. Handled correctly, this treatment can ensure a relatively high quality of life for dogs living with the disease.

Where does CBD come into the picture?

There’s some indication that CBD may directly affect the size and growth of tumors, which could be good news for dogs with Cushing’s as a result of cancerous growths. However, the real value of CBD products for dogs overproducing cortisol is threefold:

CBD oil may be able to counteract the side effects of drugs commonly prescribed to dogs for Cushing’s. These include reduced appetite, vomiting, and lack of energy.

Second, CBD oil may be able to counteract the effects of increased cortisol levels. Working through the endocannabinoid system, CBD is able to affect receptors in the brain, nervous system, and gastrointestinal tract, reducing inflammation and irritation.

And finally, some research suggests that CBD oil may be able to help reduce hormonal imbalances and lower cortisol levels in the body. Cannabinoid receptors, which are affected by CBD, are expressed throughout the body, including the pituitary gland, and are able to influence the stress response.

And does it work?

The only true way to find out if CBD will have a beneficial effect on your dog is to try it out—starting with small daily dosages and moving from there. For some dogs, CBD may not prove effective, but the chances of your pup having a negative reaction are small to non-existent.

Until clinical evidence catches up with mainstream use, we won’t know for sure whether CBD is a viable treatment for Cushing’s disease in dogs. But, given substantial proof of CBD’s ability to work on cortisol levels through the endocrine and endocannabinoid systems, there’s definitely a good reason to be optimistic.

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Cortisol is a naturally occurring hormone related to the management of stress inside the body.

Cushing’s disease occurs when cortisol levels increase, due to the presence of a tumor or other disruption to the adrenal or pituitary glands.

CBD is unlikely to cure Cushing’s disease, but it should help with many of the resulting symptoms, as well as reducing levels of cortisol and overall hormone imbalances in a dog’s body.

While CBD is a good option for pet owners looking to supplement their dog’s treatment plan, it shouldn’t replace any existing treatment without extensive prior consultation with a veterinarian.

Best CBD Oil For Dogs With Cushing’s

Is your dog suffering from Cushing’s disease? Whether your loyal companion is potentially developing recent symptoms or has been fighting Cushing’s disease for years, CBD oil can offer some relief. Some dog breeds are at a much higher risk for Cushing’s disease that could develop sooner rather than later.

For these dogs, starting an early CBD oil regimen can help them enjoy more fun and active days.

CBD Oil For Dogs With Cushing’s Disease

Cannanine™ CBD oil for dogs with Cushing’s disease can help your furry friend reduce the pain they may be experiencing due to Cushing’s disease symptoms or treatments. Our hemp oil is specifically formulated to help improve mobility, reduce pain, and reduce inflammation.

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What is Cushing’s Disease in Dogs?

Within the bodies of all mammals are the adrenal glands. These glands are located on the top of the kidneys and they are essential for all mammals to live. The adrenal glands are responsible for regulating blood pressure, blood volume, and vascular tone. They also produce hormones that help regulate metabolism, the immune system, and the stress response. Cushing’s disease is essentially when the adrenal glands, inside of a dog’s body, begin to overproduce cortisol. When too much cortisol is produced, there can be many adverse effects.

The adverse effects can range from kidney damage, diabetes, kidney failure, and even death. If a dog develops Cushing’s disease, it could be a sign that a tumor has grown either on the pituitary gland or the adrenal glands themselves. There are three main types of Cushing’s disease to be aware of. There is pituitary-dependent, adrenal-dependent, and Iatrogenic Cushing’s syndrome.

The most common is pituitary-dependent Cushing’s disease, which as mentioned earlier, is caused by a tumor on the pituitary gland. Adrenal-dependent Cushing’s disease involves a tumor that forms directly on the adrenal glands. Latrogenic Cushing’s disease is the rarest form of the disease as it is a direct result of the overuse of steroids.

What are the Symptoms of Cushing’s Disease in Dogs?

Cushing’s disease is a serious condition that could lead to serious health issues including kidney damage, blood clots, high blood pressure, diabetes, and loss of life. It is important that you be able to identify the early warning signs so that you can seek proper care for your pet to prevent the worst. Symptoms may include one or more of the following:

Increased appetite: This may be one of the harder symptoms to recognize. Sometimes dogs simply will eat whatever you put in front of them. However, if you notice a change in behavior around feeding time, for example, a constant whining for more food after they have finished their typical portion, or becoming aggressive when feeding time is over, they may be telling you that their appetite is not being entirely satisfied.

Thinning of skin: A dog that has thinning skin will have skin that begins to become fragile, abnormally soft, stretchy, or loose. You may even notice hanging folds of skin that were not present before. The thinning of the skin is a major indicator of Cushing’s disease.

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Loss of hair: If your dog begins to lose an alarming amount of hair that is beyond normal shedding, it could be a symptom of Cushing’s disease that you will want to pay attention to. The hair may often fall out in clumps during grooming sessions.

Urination issues: If you notice a dramatic increase in the number of times your dog needs to urinate or they urinate in the home because they are unable to control their urination, then you may want to take notice and contact your veterinarian

Enlarged abdomen: If your dog’s abdomen becomes distended or enlarged beyond its normal contour, or it becomes hard and has an unusual shape, it could be a sign that your dog could be experiencing one of the more serious symptoms of Cushing’s disease.

Lethargy: Dogs with visible lethargy and muscle weakness could be showing signs of Cushing’s disease. If your dog is abnormally mopy or unable to play or go for long walks like normal, it could be a sign of fatigue that comes from the disease.

If you begin witnessing any of these symptoms, you should contact your veterinarian right away. It may not be Cushing’s disease at all and it may be something much more minor, however, it is better to err on the side of caution.

Does CBD oil help with Cushing’s in dogs?

CBD oil has the ability to be extremely helpful for dogs who may be experiencing Cushing’s disease. The main ways that CBD oil can help with Cushing in dogs include addressing hormonal imbalances, attacking tumors, and alleviating painful and uncomfortable symptoms of the disease. Let us look in more detail at how CBD can be helpful in these three main ways.

Hormonal imbalances: The endocannabinoid system contains two receptors, the CB1 and CB2 receptors. CBD works directly with those receptors to bring balance to the body. The CB1 receptor is directly linked to the adipose tissue, liver, and adrenal glands, among other things. CBD oil can work to correct hormonal imbalances in the body that may be contributing to the progression and severity of Cushing’s disease.

Attacking tumors: CBD oil has been linked to creating natural cell death in cancer cells and tumors. Additionally, CBD oil can work to stop the creation of blood vessels that help the tumor grow.

Alleviating symptoms: CBD oil can work to alleviate some of the pain, discomfort, and anxiety your dog may be experiencing when grappling with Cushing’s disease. Additionally, CBD oil can directly help with the skin and fur-related symptoms of the disease by providing extra strength and support.

These are just a few of the ways CBD oil can help with Cushing’s in dogs. Aside from the benefits listed above, CBD oil can provide both anti-inflammatory support while helping to expel free radicals from the body that may be exacerbating the disease.

What is the best treatment for Cushing’s disease in dogs?

Since Cushing’s disease is caused by a tumor, there is always the option of surgically removing the tumor. However, the tumor’s location and the extent of the growth will determine whether or not surgery is feasible. If the tumor is located on the adrenal glands, then a skilled veterinarian may be able to remove the tumor quite easily. If the tumor is located on the pituitary gland, then medication is a much more likely option. The most commonly used drugs to treat Cushing’s disease are trilostane and mitotane. Always consult a veterinarian before mixing medications, however, CBD oil used in tandem with one of these drugs could be quite helpful. Not only can the CBD oil alleviate some of the symptoms related with Cushing’s disease, it could help subdue some of the negative side-effects associated with the medication.

Are dogs with Cushing’s in pain?

Cushing’s disease itself is not directly causing pain to the dog, however, some of the symptoms and particulars of the disease can be. For example, if Cushing’s disease is not properly medicated or treated, it can lead to severe kidney infections which can cause great pain and discomfort.

Dosage for CBD for Cushing’s Disease in Dogs

If you are thinking about starting your dog on a CBD oil regiment, it is best to start slow with the dosage to see how they react. The size of the dose depends entirely on the size of the dog, however, you can start with a dose somewhere between 35 to 50 mg once a day. 35 mg is ideal for smaller breeds where 50 mg may be more appropriate for large breeds. You can either serve the CBD oil directly, mix with your pet’s food, or consider purchasing CBD doggie treats.

Research on CBD for Cushing’s Disease in Dogs

There has been plenty of research on the safety of, and the effectiveness of using CBD oil to help dog’s we may be experiencing Cushing’s disease. Additionally, CBD oil has been found to help kill tumors and to prevent the blood vessels that feed the tumor from growing. Research has been conducted by the A.B. Hancock Jr. Memorial Laboratory for Cancer Research, Vanderbilt Institute of Chemical Biology, Vanderbilt Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, and the Department of Physiology, School of Medicine, at Southern Illinois University. The latter specifically studied the effects of CBD on hormonal imbalances while all the former studied the ability of CBD to attack and kill cancer cells and tumors.

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Can CBD Help a Dog with Cushing’s Disease?

Dogs who have been diagnosed with Cushing’s Disease display a variety of symptoms that make this health condition a serious issue for concerned pet owners. In an effort to help their canine friend find relief, many owners have researched and started administering CBD oil for their dog with Cushing’s Disease. Because it has become a popular treatment option, it’s good to be informed about canine Cushing’s Disease, and CBD oil for Cushing’s Disease in dogs as a medical route.

What is Canine Cushing Disease?

Cushing’s Disease, or Cushing’s Syndrome is a health issue that occurs when a dog’s body produces too much cortisol. While cortisol is a necessary hormone that is responsible for stress response, weight management, blood sugar levels, and the ability to fight infections, too much or too little can lead to lasting health issues.

Cushing’s Disease is not an easy condition to diagnose, being that many of the symptoms associated with it mimic other diseases and conditions. However, once Cushing’s Disease is diagnosed, there are options to consider that will help a dog live a healthier life. In some situations, surgery can cure Cushing’s Disease by removing the disease-causing tumors on the adrenal or pituitary glands. However, not every dog is a candidate for surgery. When operations are not a viable treatment, medication is recommended in order to control canine cortisol levels.

Symptoms of Canine Cushing’s Disease

A dog with Cushing’s Disease might experience a variety of different symptoms, some of which may include

  • Increased thirst
  • Increased appetite
  • Increased urination
  • Hair loss
  • Thinning skin
  • Decreased activity
  • Increased fatigue
  • Bloating or “potbelly”
  • Frequent panting
  • Skin infections

CBD Oil for a Dog with Cushing Disease

If surgery is not a viable option for Cushing’s Disease treatment, medication is often the next step in the treatment process, though there are sometimes issues related to this approach as well. It’s not uncommon for medications that treat Cushing’s Disease to be hard on a dog’s liver, and for this reason, many dog owners seek a more natural treatment option.

In the search for natural treatments, CBD oil for dogs with Cushing’s Disease is often researched and considered. But what is CBD oil?

CBD is an abbreviated term that’s short for cannabidiol, which is a compound that is derived from the cannabis sativa plant. Though it is found in the same herb that produces THC-containing cannabis, CBD is not psychoactive and will not cause the “high” sensation associated with marijuana.

Instead, CBD oil is often used to treat chronic pain affecting both the musculoskeletal system and nervous system, and other health conditions that impact both human beings and domestic animals like dogs and cats.

Can You Treat Canine Cushing Disease with CBD?

CBD oil has been and is currently being used by many owners to treat Cushing’s Disease in their dogs. Because of its unique properties, CBD oil can treat Cushing’s disease in two different ways. It can be used to correct the hormonal imbalances caused by the pituitary or adrenal tumors in canine Cushing’s Disease, or it may even shrink the tumors that are causing the hormonal imbalance in the first place.

CBD Oil and Hormonal Imbalance in Cushing Disease

CBD oil for dogs with Cushing’s Disease can help reduce the symptoms brought on by hormonal imbalance by working to regulate the body’s hormones. Using CBD oil as a treatment can help a dog create enough hormones to balance its hormonal fluctuations, thus ensuring that enough of each hormone is being produced. With the correct number of active, healthy hormones, a dog’s body will begin to behave normally, despite having Cushing’s Disease.

CBD Oil and Tumor Shrinkage in Cushing Disease

Using CBD oil for dogs with Cushing’s Disease can work beyond treating hormonal imbalances in some cases. According to studies, CBD oil has been shown to reduce the size of cancerous and noncancerous tumors, including the tumors associated with Cushing’s Disease.

Because of the ability to shrink tumors, even to the point of completely eliminating them in some patients, CBD oil for dogs with Cushing’s Disease is likely to be an invaluable treatment option. Once the tumors have shrunk or been eliminated, the hormonal imbalance that causes the pet’s unpleasant symptoms will then be reduced or eliminated as well.

Considering CBD Oil for Cushing Disease in Dogs?

Pet owners who are thinking about using CBD oil to help alleviate the symptoms of Cushing’s Disease in their dogs should first discuss their option with their pet’s veterinary doctor. While CBD oil is not harmful to a pet’s health, it’s still beneficial to get the most out of the pet’s treatment by using it alongside a doctor’s recommendation. This way, veterinary professionals and dog owners can monitor the dog’s treatment together and gauge improvements as they develop. Ask your chosen veterinary doctor about using CBD oil for your dog with Cushing’s Disease at your next visit to learn more about this treatment option.

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