Best CBD Oil For Lung Cancer

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May be worth further exploring cannabinoids as potential cancer treatment, say researchers It may be worth exploring further the use of cannabidiol (‘CBD’) oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumour shrank without the aid of conventional treatment. The body’s own endocannabinoids are […] Experts have said more research is needed to prove that self-medicating with CBD oil is what caused the woman’s tumor to shrink.

Daily use of cannabidiol (‘CBD’) oil may be linked to lung cancer regression

It may be worth exploring further the use of cannabidiol (‘CBD’) oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumour shrank without the aid of conventional treatment.

The body’s own endocannabinoids are involved in various processes, including nerve function, emotion, energy metabolism, pain and inflammation, sleep and immune function.

Chemically similar to these endocannabinoids, cannabinoids can interact with signalling pathways in cells, including cancer cells. They have been studied for use as a primary cancer treatment, but the results have been inconsistent.

Lung cancer remains the second most common cancer in the UK. Despite treatment advances, survival rates remain low at around 15% five years after diagnosis. And average survival without treatment is around 7 months.

The report authors describe the case of a woman in her 80s, diagnosed with non-small cell lung cancer. She also had mild chronic obstructive pulmonary disease (COPD), osteoarthritis, and high blood pressure, for which she was taking various drugs.

She was a smoker, getting through around a pack plus of cigarettes every week (68 packs/year).

Her tumour was 41 mm in size at diagnosis, with no evidence of local or further spread, so was suitable for conventional treatment of surgery, chemotherapy, and radiotherapy. But the woman refused treatment, so was placed under ‘watch and wait’ monitoring, which included regular CT scans every 3-6 months.

These showed that the tumour was progressively shrinking, reducing in size from 41 mm in June 2018 to 10 mm by February 2021, equal to an overall 76% reduction in maximum diameter, averaging 2.4% a month, say the report authors.

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When contacted in 2019 to discuss her progress, the woman revealed that she had been taking CBD oil as an alternative self-treatment for her lung cancer since August 2018, shortly after her original diagnosis.

She had done so on the advice of a relative, after witnessing her husband struggle with the side effects of radiotherapy. She said she consistently took 0.5 ml of the oil, usually three times a day, but sometimes twice.

The supplier had advised that the main active ingredients were Δ9-­tetrahydrocannabinol (THC) at 19.5%, cannabidiol at around 20%, and tetrahydrocannabinolic acid (THCA) at around 24%.

The supplier also advised that hot food or drinks should be avoided when taking the oil as she might otherwise feel stoned. The woman said she had reduced appetite since taking the oil but had no other obvious ‘side effects’. There were no other changes to her prescribed meds, diet, or lifestyle. And she continued to smoke throughout.

This is just one case report, with only one other similar case reported, caution the authors. And it’s not clear which of the CBD oil ingredients might have been helpful.

“We are unable to confirm the full ingredients of the CBD oil that the patient was taking or to provide information on which of the ingredient(s) may be contributing to the observed tumour regression,” they point out.

And they emphasise: “Although there appears to be a relationship between the intake of CBD oil and the observed tumour regression, we are unable to conclusively confirm that the tumour regression is due to the patient taking CBD oil.”

Cannabis has a long ‘medicinal’ history in modern medicine, having been first introduced in 1842 for its analgesic, sedative, anti-inflammatory, antispasmodic and anticonvulsant effects. And it is widely believed that cannabinoids can help people with chronic pain, anxiety and sleep disorders; cannabinoids are also used in palliative care, the authors add.

“More research is needed to identify the actual mechanism of action, administration pathways, safe dosages, its effects on different types of cancer and any potential adverse side effects when using cannabinoids,” they conclude.

Notes for editors
Please note: out of respect for patient confidentiality we don’t have the names or contact details of the cases reported in this journal.

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Funding: None declared

Link to Academy of Medical Sciences labelling system
https://press.psprings.co.uk/ AMSlabels.pdf

Externally peer reviewed? Yes
Evidence type: Single case report
Subjects: People

Woman’s Lung Cancer Shrinking After She Took CBD Oil Prompts Caution From Scientists

Scientists have advised caution after a report emerged of a woman whose lung cancer tumor shrank after she took regular doses of CBD oil.

CBD oil, which is a non-psychoactive chemical extracted from the hemp or cannabis plant, is linked to several possible health benefits such as pain relief and anxiety reduction.

People have also wondered whether CBD could be used as a cancer treatment, but this link remains inconclusive, according to MedicalNewsToday.

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A case report was published in the British Medical Journal on October 14 involving a woman in her 80s who was diagnosed with lung cancer in 2018 after she went to doctors with a persistent cough.

The woman, a 68-pack-a-year smoker, was offered treatment for her cancer including surgery and radiotherapy, but she declined both, so doctors decided to simply watch and wait by carrying out regular scans.

According to the case report, regular CT scans over the following two-and-a-half years showed that her lung tumor appeared to be shrinking over time, despite the fact that the woman was continuing to smoke and was not receiving any conventional treatment.

The lesion in her lungs was measured at 41 millimeters in June 2018 and had reduced to 10 millimeters by February 2021.

When doctors contacted her to discuss this, she revealed that she had been taking “CBD oil” as a self-treatment after being advised to do so by a family member shortly after her 2018 diagnosis.

The woman was taking 0.5 milliliters of the oil two to three times per day by ingesting it. The case report authors note that the oil “appears to have had a positive effect on her disease” but couldn’t conclusively confirm this.

“Although there is clearly a potential for cannabinoids to be used as a primary or as an adjunct form of cancer treatment, further research is required to identify exactly which compound works against which specific cancer cell type,” the report states.

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It also notes that previous studies have “failed to agree on the usefulness of cannabinoids as a cancer treatment.”

Meanwhile, scientists not involved in the case report have said that while the case appears encouraging, it should be taken with caution.

Professor David Nutt, The Edmond J Safra Chair in Neuropsychopharmacology at Imperial College London, told the Science Media Centre (SMC) that the example is “one of many such promising single case reports of medical cannabis self-treatment for various cancers,” but added: “A case report itself is not sufficient to give any form of proof that one thing caused the other—we need trials for that.”

Professor Edzard Ernst, Emeritus Professor of Complementary Medicine at the University of Exeter, echoed the point, telling the SMC that while some case reports into cancer and cannabis extracts have been encouraging, “case reports cannot be considered to be reliable evidence.”

One other issue with this case was that the woman had used CBD oil that also contained THC—the chemical in cannabis that causes people to feel high.

“This type of product is very different to most CBD oils which predominantly contain CBD,” Dr. Tom Freeman, senior lecturer and director of the Addiction and Mental Health Group at the University of Bath, told SMC.

Indeed, the case report authors note that it is difficult to conclude whether the THC in the woman’s oil contributed to the tumor reduction or if it was just the CBD component that may have had a positive effect.

Freeman added that “people with lung cancer should always seek guidance from a healthcare professional.”

A stock photo shows a small bottle of oil against a backdrop of cannabis plants. CBD, which can take the form of oil, has been linked to various potential health benefits but it is still not known whether it can be used to treat cancer. Tinnakorn Jorruang/Getty

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